The value of 99mTc-MAA SPECT/CT for lung shunt estimation in 90Y radioembolization: a phantom and patient study

The value of 99mTc-MAA SPECT/CT for lung shunt estimation in 90Y radioembolization: a phantom and patient study

Abstract Background A major toxicity concern in radioembolization therapy of hepatic malignancies is radiation-induced pneumonitis and sclerosis due to hepatopulmonary shunting of 90Y microspheres. Currently, 99mTc macroaggregated albumin (99mTc-MAA) imaging is used to estimate the lung shunt fracti...

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Bibliographic Details
Main Authors: Jonathan D. Allred, Jeremy Niedbala, Justin K. Mikell, Dawn Owen, Kirk A. Frey, Yuni K. Dewaraja
Format: Article
Language:English
Published: SpringerOpen 2018-06-01
Series:EJNMMI Research
Subjects:
90Y PET/CT
Transarterial radioembolization (TARE)
Lung shunt
99mTc-MAA SPECT/CT
Online Access:http://link.springer.com/article/10.1186/s13550-018-0402-8

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http://link.springer.com/article/10.1186/s13550-018-0402-8

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