Reversible differentiation of immortalized human bladder smooth muscle cells accompanied by actin bundle reorganization.

Previous studies have shown that phenotypic modulation of smooth muscle cells (SMCs) plays a pivotal role in human diseases. However, the molecular mechanisms underlying the reversible differentiation of SMCs remain elusive particularly because cultured SMCs that reproducibly exhibit bidirectional p...

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Bibliographic Details
Main Authors: Naohiro Hashimoto, Tohru Kiyono, Fumihito Saitow, Minoru Asada, Masaki Yoshida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5648286?pdf=render