Increased Locomotor Activity and Non-Selective Attention and Impaired Learning Ability in SD Rats after Lentiviral Vector-Mediated RNA Interference of Homer 1a in the Brain

Increased Locomotor Activity and Non-Selective Attention and Impaired Learning Ability in SD Rats after Lentiviral Vector-Mediated RNA Interference of Homer 1a in the Brain

<p>Our previous studies found that Homer 1a, a scaffolding protein localized at the post-synaptic density (PSD) of glutamatergic excitatory synapses, is significantly down-regulated in the brain of spontaneous hypertensive rats (SHR), an animal model of attention deficit hyperactivity disorder...

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Bibliographic Details
Main Author: Qin Hong, Lei Yang, Min Zhang, Xiao-Qin Pan, Mei Guo, Li Fei, Mei-Ling Tong, Rong-Hua Chen, Xi-Rong Guo, Xia Chi
Format: Article
Language:English
Published: Ivyspring International Publisher 2013-01-01
Series:International Journal of Medical Sciences
Online Access:http://www.medsci.org/v10p0090.htm

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http://www.medsci.org/v10p0090.htm

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