Transient reduction of DNA methylation at the onset of meiosis in male mice

Transient reduction of DNA methylation at the onset of meiosis in male mice

Abstract Background Meiosis is a specialized germ cell cycle that generates haploid gametes. In the initial stage of meiosis, meiotic prophase I (MPI), homologous chromosomes pair and recombine. Extensive changes in chromatin in MPI raise an important question concerning the contribution of epigenet...

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Bibliographic Details
Main Authors: Valeriya Gaysinskaya, Brendan F. Miller, Chiara De Luca, Godfried W. van der Heijden, Kasper D. Hansen, Alex Bortvin
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Epigenetics & Chromatin
Subjects:
DNA methylation
Hemimethylation
Spermatogenesis
LINE-1
Retrotransposon
Mouse
Online Access:http://link.springer.com/article/10.1186/s13072-018-0186-0

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http://link.springer.com/article/10.1186/s13072-018-0186-0

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