Determination of hepatic 3-hydroxy-3-methylglutaryl CoA reductase activity in man

Procedures were developed for the determination of the activity of the microsomal enzyme 3-hydroxy-3-methylglutaryl CoA reductase (HMG CoA reductase, EC 1.1.1.34) in human liver. The enzyme assay could be carried out with as little as 20 mg of fresh liver tissue, thus making the method applicable to...

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Bibliographic Details
Main Authors: G. Nicolau, S. Shefer, G. Salen, E.H. Mosbach
Format: Article
Language:English
Published: Elsevier 1974-01-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520368383