Field Effect Transistor Biosensor Using Antigen Binding Fragment for Detecting Tumor Marker in Human Serum

Field Effect Transistor Biosensor Using Antigen Binding Fragment for Detecting Tumor Marker in Human Serum

Detection of tumor markers is important for cancer diagnosis. Field-effect transistors (FETs) are a promising method for the label-free detection of trace amounts of biomolecules. However, detection of electrically charged proteins using antibody-immobilized FETs is limited by ionic screening by the...

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Bibliographic Details
Main Authors: Shanshan Cheng, Kaori Hotani, Sho Hideshima, Shigeki Kuroiwa, Takuya Nakanishi, Masahiro Hashimoto, Yasuro Mori, Tetsuya Osaka
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Materials
Subjects:
antigen binding fragment
label-free detection
field effect transistor
immunosensor
Langmuir-type adsorption model
Online Access:http://www.mdpi.com/1996-1944/7/4/2490

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http://www.mdpi.com/1996-1944/7/4/2490

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