CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration.

Activated chemokine receptor initiates inside-out signaling to transiently trigger activation of integrins, a process involving multiple components that have not been fully characterized. Here we report that GM-CSF/IL-3/IL-5 receptor common beta-chain-associated protein (CBAP) is required to optimiz...

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Bibliographic Details
Main Authors: Yun-Jung Chiang, Kun-Chin Ho, Chien-Tsang Sun, Jeng-Jiann Chiu, Fang-Jen Lee, Fang Liao, Hsin-Fang Yang-Yen, Jeffrey Jong-Young Yen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3631140?pdf=render