The formation of the Bicoid morphogen gradient requires protein movement from anteriorly localized mRNA.

The Bicoid morphogen gradient directs the patterning of cell fates along the anterior-posterior axis of the syncytial Drosophila embryo and serves as a paradigm of morphogen-mediated patterning. The simplest models of gradient formation rely on constant protein synthesis and diffusion from anteriorl...

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Bibliographic Details
Main Authors: Shawn C Little, Gašper Tkačik, Thomas B Kneeland, Eric F Wieschaus, Thomas Gregor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21390295/pdf/?tool=EBI