GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells

<p>Abstract</p> <p>Background</p> <p>Growth-differentiation factor-15 (GDF-15) is a stress-responsive, transforming growth factor-β-related cytokine, which has recently been reported to be elevated in serum of patients with idiopathic pulmonary arterial hypertension (IP...

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Main Authors: Sauer Clemens, Lehmann Ulrich, Laenger Florian, Rische Johanna, Maegel Lavinia, Bockmeyer Clemens L, Kempf Tibor, Jonigk Danny, Nickel Nils, Greer Mark, Welte Tobias, Hoeper Marius M, Golpon Heiko A
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/12/1/62