ABT-869, a promising multi-targeted tyrosine kinase inhibitor: from bench to bedside

<p>Abstract</p> <p>Tyrosine Kinase Inhibitors (TKI) have significantly changed the landscape of current cancer therapy. Understanding of mechanisms of aberrant TK signaling and strategies to inhibit TKs in cancer, further promote the development of novel agents.</p> <p>...

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Bibliographic Details
Main Authors: Goh Boon-Cher, Zhou Jianbiao, Albert Daniel H, Chen Chien-Shing
Format: Article
Language:English
Published: BMC 2009-07-01
Series:Journal of Hematology & Oncology
Online Access:http://www.jhoonline.org/content/2/1/33