The Relationship between EGFR Mutations and Response and Prognosis of Tyrosine Kinase Inhibitors in Advanced Non-small-cell Lung Cancer

The Relationship between EGFR Mutations and Response and Prognosis of Tyrosine Kinase Inhibitors in Advanced Non-small-cell Lung Cancer

Background and objectives It has been proven that epigermal growth factor receptor (EGFR) signal pathway plaied an important role in the oncogenesis and development of non-small cell lung cancer (NSCLC). EGFR tyrosine kinase inhibitors (EGFR-TKIs) are currently investigated in the treatment of NSCLC...

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Bibliographic Details
Main Authors: Xuebing LI, Lili GUO, Jinghui WANG, Qiyi MENG, Mingzhi LI, Mengzhao WANG, Heling SHI, Yuankai SHI, Chunyan ZHANG, Zan LIU, Yuhua WU, Junfang TANG, Wei WU, Zhe LIU, Wentao YUE, Hui WANG, Yunzhong ZHU, Xinyong ZHANG, Liyan XU
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2008-04-01
Series:Chinese Journal of Lung Cancer
Subjects:
Lung neoplasms
Epidermal growth factor receptor
Genes mutation
Protein-tyrosine kinases
Therapeutics
Online Access:http://www.lungca.org/index.php?journal=01&page=article&op=view&path%5B%5D=10.3779%2Fj.issn.1009-3419.2008.02.016&path%5B%5D=51

Internet

http://www.lungca.org/index.php?journal=01&page=article&op=view&path%5B%5D=10.3779%2Fj.issn.1009-3419.2008.02.016&path%5B%5D=51

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