Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells

Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells

Innate lymphoid cells (ILCs) have been shown to be depleted during HIV-1 infection. Here the authors show that ILC loss is associated with CD4 depletion and gastrointestinal damage in a primate model of SIV infection.

Bibliographic Details
Main Authors: Joseph C. Mudd, Kathleen Busman-Sahay, Sarah R. DiNapoli, Stephen Lai, Virginia Sheik, Andrea Lisco, Claire Deleage, Brian Richardson, David J. Palesch, Mirko Paiardini, Mark Cameron, Irini Sereti, R. Keith Reeves, Jacob D. Estes, Jason M. Brenchley
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05528-3

Internet

https://doi.org/10.1038/s41467-018-05528-3

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