Multifaceted Role of Pneumolysin in the Pathogenesis of Myocardial Injury in Community-Acquired Pneumonia

Multifaceted Role of Pneumolysin in the Pathogenesis of Myocardial Injury in Community-Acquired Pneumonia

Pneumolysin (PLY), a member of the family of Gram-positive bacterial, cholesterol-dependent, β-barrel pore-forming cytolysins, is the major protein virulence factor of the dangerous respiratory pathogen, Streptococcus pneumoniae (pneumococcus). PLY plays a major role in the pathogenesis of community...

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Bibliographic Details
Main Authors: Ronald Anderson, Jan G. Nel, Charles Feldman
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:International Journal of Molecular Sciences
Subjects:
cardiovascular events
cholesterol-dependent cytolysins
community-acquired pneumonia
liposomes
macrolide antibiotics
neutrophils
neutrophil extracellular traps
platelets
pneumolysin antagonists
vaccines
Online Access:http://www.mdpi.com/1422-0067/19/4/1147

Internet

http://www.mdpi.com/1422-0067/19/4/1147

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