Prostaglandin E2 secreted from feline adipose tissue-derived mesenchymal stem cells alleviate DSS-induced colitis by increasing regulatory T cells in mice

Prostaglandin E2 secreted from feline adipose tissue-derived mesenchymal stem cells alleviate DSS-induced colitis by increasing regulatory T cells in mice

Abstract Background Inflammatory bowel disease (IBD) is an intractable autoimmune disease, relatively common in cats, with chronic vomiting and diarrhea. Previous studies have reported that mesenchymal stem cells (MSCs) alleviate inflammation by modulating immune cells. However, there is a lack of r...

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Bibliographic Details
Main Authors: Ju-Hyun AN, Woo-Jin SONG, Qiang LI, Sang-Min KIM, Ji-In YANG, Min-Ok RYU, A Ryung NAM, Dong Ha BHANG, Yun-Chan JUNG, Hwa-Young YOUN
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Veterinary Research
Subjects:
Cytokines
Feline mesenchymal stem cells
Immunomodulation
PBMC
Prostaglandin E2
FOXP+ Treg
Online Access:http://link.springer.com/article/10.1186/s12917-018-1684-9

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http://link.springer.com/article/10.1186/s12917-018-1684-9

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