Distinct roles of α- and βCaMKII in controlling long-term potentiation of GABAA-receptor mediated transmission in murine Purkinje cells

Distinct roles of α- and βCaMKII in controlling long-term potentiation of GABAA-receptor mediated transmission in murine Purkinje cells

Calcium/Calmodulin-dependent kinase type II (CaMKII) is essential for various forms of synaptic plasticity. The predominant α- and βCaMKII isoforms have both been shown to contribute to specific forms of plasticity at excitatory synapses, but little is known about their functions at inhibitory synap...

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Bibliographic Details
Main Authors: Zhenyu eGao, Geeske M van Woerden, Ype eElgersma, Chris I De Zeeuw, Freek eHoebeek
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Cerebellum
CaMKII
plasticity
Purkinje cell
GABAAR
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00016/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00016/full

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