The HLTF–PARP1 interaction in the progression and stability of damaged replication forks caused by methyl methanesulfonate
Abstract Human HLTF participates in the lesion-bypass mechanism through the fork reversal structure, known as template switching of post-replication repair. However, the mechanism by which HLTF promotes the replication progression and fork stability of damaged forks remains unclear. Here, we identif...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2020-12-01
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| Series: | Oncogenesis |
| Online Access: | https://doi.org/10.1038/s41389-020-00289-5 |