miR-125a suppresses viability and glycolysis and induces apoptosis by targeting Hexokinase 2 in laryngeal squamous cell carcinoma

miR-125a suppresses viability and glycolysis and induces apoptosis by targeting Hexokinase 2 in laryngeal squamous cell carcinoma

Abstract Background miR-125a usually functions as a tumor suppressor in cancers. However, the role of miR-125a in laryngeal squamous cell carcinoma (LSCC) has not been determined. Methods qRT-PCR was applied to measure the expression of miR-125a and HK2 mRNA in LSCC tissues and cells. CCK-8 kit and...

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Bibliographic Details
Main Authors: Zhanwei Sun, Wenqi Zhang, Qian Li
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Cell & Bioscience
Subjects:
miR-125a
Proliferation
Glycolysis
Apoptosis
HK2
Online Access:http://link.springer.com/article/10.1186/s13578-017-0178-y

Internet

http://link.springer.com/article/10.1186/s13578-017-0178-y

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