Synergistic Enhancement of Cancer Therapy Using HDAC Inhibitors: Opportunity for Clinical Trials

Synergistic Enhancement of Cancer Therapy Using HDAC Inhibitors: Opportunity for Clinical Trials

Chemotherapy is one of the most established and effective treatments for almost all types of cancer. However, the elevated toxicity due to the non-tumor-associated effects, development of secondary malignancies, infertility, radiation-induced fibrosis and resistance to treatment limit the effectiven...

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Bibliographic Details
Main Authors: Lourdes Hontecillas-Prieto, Rocío Flores-Campos, Andrew Silver, Enrique de Álava, Nabil Hajji, Daniel J. García-Domínguez
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Genetics
Subjects:
histone deacetylases
HDAC inhibitors (HDACis)
combination treatment
cancer
clinical trials
preclinical studies
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.578011/full

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https://www.frontiersin.org/article/10.3389/fgene.2020.578011/full

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