Metabolic Function of a Suboptimal Transplanted Islet Mass in Nonhuman Primates on Rapamycin Monotherapy
Although islet transplantation may restore insulin independence to individuals with type 1 diabetes mellitus, most have abnormal glucose tolerance. We asked whether the defective glucose tolerance is due to inadequate β-cell mass or to impaired insulin sensitivity. We performed metabolic studies on...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2012-06-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368911X603620 |