Transfection with CXCR4 potentiates homing of mesenchymal stem cells in vitro and therapy of diabetic retinopathy in vivo

AIM: To investigate the effect of the overexpression of C-X-C chemokine receptor type 4 (CXCR4) on homing of mesenchymal stem cells (MSCs) in vitro and therapeutic effects of diabetic retinopathy (DR) in vivo. METHODS: MSCs were infected by lentivirus constructed with CXCR4. The expression of CXCR4...

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Bibliographic Details
Main Authors: Jian Wang, Wei Zhang, Guang-Hui He, Bin Wu, Song Chen
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2018-05-01
Series:International Journal of Ophthalmology
Subjects:
772
Online Access:http://www.ijo.cn/en_publish/2018/5/20180508.pdf