p53 Stabilization induces cell growth inhibition and affects IGF2 pathway in response to radiotherapy in adrenocortical cancer cells.

p53 Stabilization induces cell growth inhibition and affects IGF2 pathway in response to radiotherapy in adrenocortical cancer cells.

Adrenocortical carcinoma (ACC) is a very rare endocrine tumour, with variable prognosis, depending on tumour stage and time of diagnosis. However, it is generally fatal, with an overall survival of 5 years from detection. Radiotherapy usefulness for ACC treatment has been widely debated and seems to...

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Bibliographic Details
Main Authors: Camilla Sampaoli, Lidia Cerquetti, Randa El Gawhary, Barbara Bucci, Donatella Amendola, Rodolfo Marchese, Silvia Misiti, Giuseppe Novelli, Vincenzo Toscano, Antonio Stigliano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3446967?pdf=render

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http://europepmc.org/articles/PMC3446967?pdf=render

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