Hypoxia Up-Regulates Galectin-3 in Mammary Tumor Progression and Metastasis.

The tumor microenvironment encompasses several stressful conditions for cancer cells such as hypoxia, oxidative stress and pH alterations. Galectin-3, a well-studied member of the beta-galactoside-binding animal family of lectins has been implicated in multiple steps of metastasis as cell-cell and c...

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Bibliographic Details
Main Authors: Joana T de Oliveira, Cláudia Ribeiro, Rita Barros, Catarina Gomes, Augusto J de Matos, Celso A Reis, Gerard R Rutteman, Fátima Gärtner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4519331?pdf=render