A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynamics.
Poxviruses include medically important human pathogens, yet little is known about the specific cellular factors essential for their replication. To identify genes essential for poxvirus infection, we used high-throughput RNA interference to screen the Drosophila kinome for factors required for vacci...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-06-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC2887478?pdf=render |