Avian-to-Human Receptor-Binding Adaptation by Influenza A Virus Hemagglutinin H4

Summary: Low-pathogenicity avian influenza viruses (LPAIVs) have caused a global concern to public health since the first novel LPAIV H7N9 outbreak occurred. The receptor-binding properties of the viral hemagglutinin are one key factor for efficient transmission and infection in humans. Recent evide...

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Bibliographic Details
Main Authors: Hao Song, Jianxun Qi, Haixia Xiao, Yuhai Bi, Wei Zhang, Ying Xu, Fei Wang, Yi Shi, George F. Gao
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717309944