Structural Insight into Archaic and Alternative Chaperone-Usher Pathways Reveals a Novel Mechanism of Pilus Biogenesis.

Gram-negative pathogens express fibrous adhesive organelles that mediate targeting to sites of infection. The major class of these organelles is assembled via the classical, alternative and archaic chaperone-usher pathways. Although non-classical systems share a wider phylogenetic distribution and a...

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Bibliographic Details
Main Authors: Natalia Pakharukova, James A Garnett, Minna Tuittila, Sari Paavilainen, Mamou Diallo, Yingqi Xu, Steve J Matthews, Anton V Zavialov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005269