A modified density gradient proteomic-based method to analyze endolysosomal proteins in cardiac tissue

A modified density gradient proteomic-based method to analyze endolysosomal proteins in cardiac tissue

Summary: The importance of lysosomes in cardiac physiology and pathology is well established, and evidence for roles in calcium signaling is emerging. We describe a label-free proteomics method suitable for small cardiac tissue biopsies based on density-separated fractionation, which allows study of...

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Bibliographic Details
Main Authors: Thamali Ayagama, Samuel J. Bose, Rebecca A. Capel, David A. Priestman, Georgina Berridge, Roman Fischer, Antony Galione, Frances M. Platt, Holger Kramer, Rebecca A.B. Burton
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:iScience
Subjects:
Porcine cardiology
Biological sciences
Biochemistry
Systems biology
Omics
Proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221009172

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http://www.sciencedirect.com/science/article/pii/S2589004221009172

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