Expression patterns of protein kinases correlate with gene architecture and evolutionary rates.

BACKGROUND:Protein kinase (PK) genes comprise the third largest superfamily that occupy approximately 2% of the human genome. They encode regulatory enzymes that control a vast variety of cellular processes through phosphorylation of their protein substrates. Expression of PK genes is subject to com...

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Bibliographic Details
Main Authors: Aleksey Y Ogurtsov, Leonardo Mariño-Ramírez, Gibbes R Johnson, David Landsman, Svetlana A Shabalina, Nikolay A Spiridonov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2572838?pdf=render