Important cardiac transcription factor genes are accompanied by bidirectional long non-coding RNAs

Important cardiac transcription factor genes are accompanied by bidirectional long non-coding RNAs

Abstract Background Heart development is a relatively fragile process in which many transcription factor genes show dose-sensitive characteristics such as haploinsufficiency and lower penetrance. Despite efforts to unravel the genetic mechanism for overcoming the fragility under normal conditions, o...

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Bibliographic Details
Main Authors: Yutaro Hori, Yoko Tanimoto, Satoru Takahashi, Tetsushi Furukawa, Kazuko Koshiba-Takeuchi, Jun K. Takeuchi
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Genomics
Subjects:
Heart development
Long non-coding RNA
Haploinsufficiency
Bidirectional promoter
Online Access:http://link.springer.com/article/10.1186/s12864-018-5233-5

Internet

http://link.springer.com/article/10.1186/s12864-018-5233-5

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