Melatonin enhances the anti-tumor effect of fisetin by inhibiting COX-2/iNOS and NF-κB/p300 signaling pathways.

Melatonin enhances the anti-tumor effect of fisetin by inhibiting COX-2/iNOS and NF-κB/p300 signaling pathways.

Melatonin is a hormone identified in plants and pineal glands of mammals and possesses diverse physiological functions. Fisetin is a bio-flavonoid widely found in plants and exerts antitumor activity in several types of human cancers. However, the combinational effect of melatonin and fisetin on ant...

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Bibliographic Details
Main Authors: Canhui Yi, Yong Zhang, Zhenlong Yu, Yao Xiao, Jingshu Wang, Huijuan Qiu, Wendan Yu, Ranran Tang, Yuhui Yuan, Wei Guo, Wuguo Deng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4085069?pdf=render

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http://europepmc.org/articles/PMC4085069?pdf=render

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