A Hypoxia-Inducible Factor Stabilizer Improves Hematopoiesis and Iron Metabolism Early after Administration to Treat Anemia in Hemodialysis Patients

A Hypoxia-Inducible Factor Stabilizer Improves Hematopoiesis and Iron Metabolism Early after Administration to Treat Anemia in Hemodialysis Patients

Roxadustat (Rox), a hypoxia-inducible factor (HIF) stabilizer, is now available for the treatment of anemia in hemodialysis (HD) patients. To investigate hematopoietic effect and iron metabolism, this study involved 30 HD patients who were initially treated with darbepoetin (DA), a conventional eryt...

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Bibliographic Details
Main Authors: Chie Ogawa, Ken Tsuchiya, Naohisa Tomosugi, Kunimi Maeda
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
hypoxia-inducible factor stabilizer
erythropoiesis
iron metabolism
hemodialysis
renal anemia
Online Access:https://www.mdpi.com/1422-0067/21/19/7153

Internet

https://www.mdpi.com/1422-0067/21/19/7153

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