Comparative transcriptional profiling of 3 murine models of SLE nephritis reveals both unique and shared regulatory networks.

To define shared and unique features of SLE nephritis in mouse models of proliferative and glomerulosclerotic renal disease.Perfused kidneys from NZB/W F1, NZW/BXSB and NZM2410 mice were harvested before and after nephritis onset. Affymetrix based gene expression profiles of kidney RNA were analyzed...

Full description

Bibliographic Details
Main Authors: Ramalingam Bethunaickan, Celine C Berthier, Weijia Zhang, Matthias Kretzler, Anne Davidson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3805607?pdf=render