Reduced Sensitivity of Influenza A (H5N1) to Oseltamivir

Reduced Sensitivity of Influenza A (H5N1) to Oseltamivir

We tested the neuraminidase drug sensitivity of clade 1 and clade 2 influenza A virus (H5N1). All viruses demonstrated similar sensitivity to zanamivir, but compared to the 2004 clade 1 viruses, the Cambodian 2005 viruses were 6-fold less sensitive and the Indonesian clade 2 viruses were up to 30-fo...

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Bibliographic Details
Main Authors: Jennifer L. McKimm-Breschkin, Paul W. Selleck, Tri Bhakti Usman, Michael A. Johnson
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2007-09-01
Series:Emerging Infectious Diseases
Subjects:
Avian influenza
H5N1
oseltamivir
zanamivir
antiviral drug resistance
neuraminidase
Online Access:https://wwwnc.cdc.gov/eid/article/13/9/07-0164_article

Internet

https://wwwnc.cdc.gov/eid/article/13/9/07-0164_article

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