Tissue factor pathway inhibitor 2 is found in skin and its C-terminal region encodes for antibacterial activity.

Tissue factor pathway inhibitor 2 is found in skin and its C-terminal region encodes for antibacterial activity.

BACKGROUND: Tissue factor pathway inhibitor 2 (TFPI-2) is a matrix-associated serine protease inhibitor with an enigmatic function in vivo. Here, we describe that TFPI-2 is present in fibrin of wounds and also expressed in skin, where it is up-regulated upon wounding. METHODOLOGY AND PRINCIPAL FINDI...

Full description

Bibliographic Details
Main Authors: Praveen Papareddy, Martina Kalle, Ole E Sørensen, Katarina Lundqvist, Matthias Mörgelin, Martin Malmsten, Artur Schmidtchen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3530512?pdf=render

Internet

http://europepmc.org/articles/PMC3530512?pdf=render

Similar Items