Structural Characterization of the RNA-Binding Protein SERBP1 Reveals Intrinsic Disorder and Atypical RNA Binding Modes

Structural Characterization of the RNA-Binding Protein SERBP1 Reveals Intrinsic Disorder and Atypical RNA Binding Modes

RNA binding proteins (RBPs) are essential for critical biological processes such as translation regulation and mRNA processing, and misfunctions of these proteins are associated with diseases such as cancer and neurodegeneration. SERBP1 (SERPINE1 mRNA Binding Protein 1) is an RBP that comprises two...

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Bibliographic Details
Main Authors: Antoine Baudin, Alma K. Moreno-Romero, Xiaoping Xu, Emily E. Selig, Luiz O. F. Penalva, David S. Libich
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
SERBP1
RNA binding protein
mRNA binding
intrinsically disordered protein
NMR
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.744707/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.744707/full

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