Anticancer Activity of Lesbicoumestan in Jurkat Cells via Inhibition of Oxidative Stress-Mediated Apoptosis and MALT1 Protease

Anticancer Activity of Lesbicoumestan in Jurkat Cells via Inhibition of Oxidative Stress-Mediated Apoptosis and MALT1 Protease

This study explores the potential anticancer effects of lesbicoumestan from <i>Lespedeza bicolor</i> against human leukemia cancer cells. Flow cytometry and fluorescence microscopy were used to investigate antiproliferative effects. The degradation of mucosa-associated lymphoid tissue ly...

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Bibliographic Details
Main Authors: Joo-Eun Lee, Fang Bo, Nguyen Thi Thanh Thuy, Jaewoo Hong, Ji Shin Lee, Namki Cho, Hee Min Yoo
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
lesbicoumestan
MALT1/NF-κB
ROS
mitochondrial depolarization
3D Jurkat cell
Online Access:https://www.mdpi.com/1420-3049/26/1/185

Internet

https://www.mdpi.com/1420-3049/26/1/185

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