Alpha-catenin-dependent recruitment of the centrosomal protein CAP350 to adherens junctions allows epithelial cells to acquire a columnar shape.

Epithelial morphogenesis involves a dramatic reorganisation of the microtubule cytoskeleton. How this complex process is controlled at the molecular level is still largely unknown. Here, we report that the centrosomal microtubule (MT)-binding protein CAP350 localises at adherens junctions in epithel...

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Bibliographic Details
Main Authors: Maria P Gavilan, Marina Arjona, Angel Zurbano, Etienne Formstecher, Juan R Martinez-Morales, Michel Bornens, Rosa M Rios
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4357431?pdf=render