Molecular characteristics and spatial distribution of adult human corneal cell subtypes

Abstract Bulk RNA sequencing of a tissue captures the gene expression profile from all cell types combined. Single-cell RNA sequencing identifies discrete cell-signatures based on transcriptomic identities. Six adult human corneas were processed for single-cell RNAseq and 16 cell clusters were bioin...

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Bibliographic Details
Main Authors: Ann J. Ligocki, Wen Fury, Christian Gutierrez, Christina Adler, Tao Yang, Min Ni, Yu Bai, Yi Wei, Guillermo L. Lehmann, Carmelo Romano
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94933-8