The PTIP-Associated Histone Methyltransferase Complex Prevents Stress-Induced Maladaptive Cardiac Remodeling.

The PTIP-Associated Histone Methyltransferase Complex Prevents Stress-Induced Maladaptive Cardiac Remodeling.

Pressure overload induces stress-induced signaling pathways and a coordinated transcriptional response that begets concentric cardiac hypertrophy. Although concentric hypertrophy initially attenuates wall stress and maintains cardiac function, continued stress can result in maladaptive cardiac remod...

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Bibliographic Details
Main Authors: Adam B Stein, Sascha N Goonewardena, Thomas A Jones, Parker J Prusick, Ahmad A Bazzi, Jane M Belyavskaya, Makayla M McCoskey, Rachel A Dandar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4441468?pdf=render

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http://europepmc.org/articles/PMC4441468?pdf=render

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