Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa

Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by recurrent abscesses, nodules, and sinus tracts in areas of high hair follicle and sweat gland density. These sinus tracts can present with purulent drainage and scar formation. Dysregulation of multiple immune path...

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Bibliographic Details
Main Authors: Paula Mariottoni, Simon W. Jiang, Courtney A. Prestwood, Vaibhav Jain, Jutamas Suwanpradid, Melodi Javid Whitley, Margaret Coates, David A. Brown, Detlev Erdmann, David L. Corcoran, Simon G. Gregory, Tarannum Jaleel, Jennifer Y. Zhang, Tamia A. Harris-Tryon, Amanda S. MacLeod
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Medicine
Subjects:
single cell sequencing
macrophage-cell
hidradenitis suppurativa
antiviral immune pathways
non-healing wounds
interferon
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.665873/full

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https://www.frontiersin.org/articles/10.3389/fmed.2021.665873/full

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