Osteogenic stimulatory conditions enhance growth and maturation of endothelial cell microvascular networks in culture with mesenchymal stem cells

To optimize culture conditions for in vitro prevascularization of tissue-engineered bone constructs, the development of organotypic blood vessels under osteogenic stimulatory conditions (OM) was investigated. Coculture of endothelial cells and mesenchymal stem cells was used to assess proangiogenic...

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Bibliographic Details
Main Authors: Torbjorn O Pedersen, Anna L Blois, Ying Xue, Zhe Xing, Michele Cottler-Fox, Inge Fristad, Knut N Leknes, James B Lorens, Kamal Mustafa
Format: Article
Language:English
Published: SAGE Publishing 2012-12-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/2041731412443236