Combining genotype improvement and statistical media optimization for isoprenoid production in E. coli.

Isoprenoids are a large and diverse class of compounds that includes many high value natural products and are thus in great demand. To meet the increasing demand for isoprenoid compounds, metabolic engineering of microbes has been used to produce isoprenoids in an economical and sustainable manner....

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Bibliographic Details
Main Authors: Congqiang Zhang, Xixian Chen, Ruiyang Zou, Kang Zhou, Gregory Stephanopoulos, Heng-Phon Too
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3790805?pdf=render