Commercially available outbred mice for genome-wide association studies.

Commercially available outbred mice for genome-wide association studies.

Genome-wide association studies using commercially available outbred mice can detect genes involved in phenotypes of biomedical interest. Useful populations need high-frequency alleles to ensure high power to detect quantitative trait loci (QTLs), low linkage disequilibrium between markers to obtain...

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Bibliographic Details
Main Authors: Binnaz Yalcin, Jérôme Nicod, Amarjit Bhomra, Stuart Davidson, James Cleak, Laurent Farinelli, Magne Østerås, Adam Whitley, Wei Yuan, Xiangchao Gan, Martin Goodson, Paul Klenerman, Ansu Satpathy, Diane Mathis, Christophe Benoist, David J Adams, Richard Mott, Jonathan Flint
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2932682?pdf=render

Internet

http://europepmc.org/articles/PMC2932682?pdf=render

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