MLST and Whole-Genome-Based Population Analysis of Cryptococcus gattii VGIII Links Clinical, Veterinary and Environmental Strains, and Reveals Divergent Serotype Specific Sub-populations and Distant Ancestors.

The emerging pathogen Cryptococcus gattii causes life-threatening disease in immunocompetent and immunocompromised hosts. Of the four major molecular types (VGI-VGIV), the molecular type VGIII has recently emerged as cause of disease in otherwise healthy individuals, prompting a need to investigate...

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Main Authors: Carolina Firacative, Chandler C Roe, Richard Malik, Kennio Ferreira-Paim, Patricia Escandón, Jane E Sykes, Laura Rocío Castañón-Olivares, Cudberto Contreras-Peres, Blanca Samayoa, Tania C Sorrell, Elizabeth Castañeda, Shawn R Lockhart, David M Engelthaler, Wieland Meyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4975453?pdf=render