Cerebrovascular Pathology in Hypertriglyceridemic APOB-100 Transgenic Mice

Cerebrovascular Pathology in Hypertriglyceridemic APOB-100 Transgenic Mice

Hypertriglyceridemia is not only a serious risk factor in the development of cardiovascular diseases, but it is linked to neurodegeneration, too. Previously, we generated transgenic mice overexpressing the human APOB-100 protein, a mouse model of human atherosclerosis. In this model we observed high...

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Bibliographic Details
Main Authors: Zsófia Hoyk, Melinda E. Tóth, Nikolett Lénárt, Dóra Nagy, Brigitta Dukay, Alexandra Csefová, Ágnes Zvara, György Seprényi, András Kincses, Fruzsina R. Walter, Szilvia Veszelka, Judit Vígh, Beáta Barabási, András Harazin, Ágnes Kittel, László G. Puskás, Botond Penke, László Vígh, Mária A. Deli, Miklós Sántha
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
apolipoprotein B-100
astroglia
blood-brain barrier
brain endothelial cell
cerebrovascular pathology
hypertriglyceridemia
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00380/full

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https://www.frontiersin.org/article/10.3389/fncel.2018.00380/full

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