The IL-17 receptor IL-17RE mediates polyIC-induced exacerbation of experimental allergic asthma

The IL-17 receptor IL-17RE mediates polyIC-induced exacerbation of experimental allergic asthma

Abstract Background The interleukin 17 receptor E (IL-17RE) is specific for the epithelial cytokine interleukin-17C (IL-17C). Asthma exacerbations are frequently caused by viral infections. Polyinosinic:polycytidylic acid (pIC) mimics viral infections through binding to pattern recognition receptors...

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Bibliographic Details
Main Authors: Giovanna Vella, Lars Lunding, Felix Ritzmann, Anja Honecker, Christian Herr, Michael Wegmann, Robert Bals, Christoph Beisswenger
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Respiratory Research
Online Access:http://link.springer.com/article/10.1186/s12931-020-01434-9

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http://link.springer.com/article/10.1186/s12931-020-01434-9

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