Rapid EC50 determination of hydrophobic toxicants in continuous droplet biomicrofluidics

Droplet-based bioassays are attractive for increasing throughput while minimizing reagent consumption. However, the choice of continuous oil phase within the bioassay can substantially alter assay outcomes when hydrophobic reagents and analytes dynamically partition between the oil and aqueous phase...

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Bibliographic Details
Main Authors: Raphael Ortiz, David C. Stuckey, Terry W.J. Steele
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Micro and Nano Engineering
Online Access:http://www.sciencedirect.com/science/article/pii/S2590007219300218