Predicting peptide-mediated interactions on a genome-wide scale.
We describe a method to predict protein-protein interactions (PPIs) formed between structured domains and short peptide motifs. We take an integrative approach based on consensus patterns of known motifs in databases, structures of domain-motif complexes from the PDB and various sources of non-struc...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-05-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4418708?pdf=render |