Treating Disorders of Consciousness With Apomorphine: Protocol for a Double-Blind Randomized Controlled Trial Using Multimodal Assessments

Treating Disorders of Consciousness With Apomorphine: Protocol for a Double-Blind Randomized Controlled Trial Using Multimodal Assessments

Background: There are few available therapeutic options to promote recovery among patients with chronic disorders of consciousness (DOC). Among pharmacological treatments, apomorphine, a dopamine agonist, has exhibited promising behavioral effects and safety of use in small-sample pilot studies. The...

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Bibliographic Details
Main Authors: Leandro R. D. Sanz, Nicolas Lejeune, Séverine Blandiaux, Estelle Bonin, Aurore Thibaut, Johan Stender, Neal M. Farber, Ross D. Zafonte, Nicholas D. Schiff, Steven Laureys, Olivia Gosseries
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Neurology
Subjects:
disorders of consciousness
unresponsive wakefulness syndrome
minimally conscious state
apomorphine
dopamine
mesocircuit
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00248/full

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https://www.frontiersin.org/article/10.3389/fneur.2019.00248/full

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