Condition-specific gene co-expression network mining identifies key pathways and regulators in the brain tissue of Alzheimer’s disease patients

Condition-specific gene co-expression network mining identifies key pathways and regulators in the brain tissue of Alzheimer’s disease patients

Abstract Background Gene co-expression network (GCN) mining is a systematic approach to efficiently identify novel disease pathways, predict novel gene functions and search for potential disease biomarkers. However, few studies have systematically identified GCNs in multiple brain transcriptomic dat...

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Bibliographic Details
Main Authors: Shunian Xiang, Zhi Huang, Tianfu Wang, Zhi Han, Christina Y. Yu, Dong Ni, Kun Huang, Jie Zhang
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Medical Genomics
Subjects:
Alzheimer’s Disease
Co-expression
Condition-specific module
Bacterial and viral infectious pathway
Online Access:http://link.springer.com/article/10.1186/s12920-018-0431-1

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http://link.springer.com/article/10.1186/s12920-018-0431-1

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