Full Genomic Sequences of H5N1 Highly Pathogenic Avian Influenza Virus in Human Autopsy Specimens Reveal Genetic Variability and Adaptive Changes for Growth in MDCK Cell Cultures

The entire H5N1 highly pathogenic avian influenza viral genomes were identified in the frozen autopsy specimens: the trachea, lung, colon, and intestinal feces from a patient who died of the disease in 2006. Phylogenetic analysis of the viral genomes showed that these viruses belonged to clade 1 and...

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Main Authors: Kantima Sangsiriwut, Pirom Noisumdaeng, Mongkol Uiprasertkul, Jarunee Prasertsopon, Sunchai Payungporn, Prasert Auewarakul, Kumnuan Ungchusak, Pilaipan Puthavathana
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2021/3890681